Eye diseases associated with abnormalities of embryologic development pax6 mutations pax6 is a homeobox gene that is vitally important to the proper development of the eye various defects in pax6 will result in various eye abnormalities ranging from glaucoma and cataracts to optic nerve and foveal hypoplasia. Investigating the embryology of the eye is clearly a more difficult area because of the relative scarcity of suitable human material and thus there is still great reliance on animal studies with the inherent difficulties in inferring parallels in human development nevertheless a great deal is known about the embryology of the human eye and together with the recent expansion in molecular . Morris j mintz embryology of the human eye american journal of clinical pathology volume 25 issue 9 1 september 1955 pages 1068 https doiorg 101093
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